[Zinc-fans] Indiscriminate Binders?

Andrew Fant fant at pobox.com
Mon Aug 6 13:24:25 PDT 2007


I know that this is kind of the opposite of what virtual screening types
normally look for, but has anyone ever generated a subset of zinc compounds that
are promiscuous binders?  I have a small project going involving binding site
prediction, and I could really use a set of likely false positives that would
still look lead-like.  If anyone has any suggestions, I would be most grateful.

Thanks,
	Andy


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